Manchester United will look to cement their position at the top of Group B when they welcome Besiktas JK to Old Trafford.
With qualification assured, the Manchester United players could be excused for putting their feet up, but for some, Wednesday night is the time to shine.
The hard work is done and United’s name is already in the hat for the knockout stages of the Champions League after a dominant display in Group B. Sir Alex Ferguson is likely to take the chance to showcase the strength of his squad for the visit of bottom of the table Besiktas, with Darron Gibson, Rafael, Gabriel Obertan, Danny Welbeck and Federico Macheda all set to start..
For Besiktas, this match is crucial for their Europa League ambitions, given that, bar a quite miraculous turnaround, their hopes of securing second place in the group are already out of the window. Mustafa Denizli's side travel to Manchester in good form, having dispatched Fenerbahce 3-0 on Saturday, to make it four wins from their last five outings.
Manchester United striker Dimitar Berbatov, who has been sidelined with a knee injury, could be in line for return despite his manager Sir Alex Ferguson apparently ruling him out of the Champions League game when he spoke at the weekend.
Darron Gibson will start in midfield while Gabriel Obertan, the £3m signing from Bordeaux in July, will also start his first European game for the club.
In addition, Rafael Da Silva will feature along with Park Ji-Sung. Danny Welbeck and Federico Macheda are likely to be on the bench but Rio Ferdinand (back), Jonny Evans (calf) and John O'Shea (ankle) are all definitely out.
Ferguson also faces a choice between Tomasz Kuszczak and Ben Foster in goal as Edwin van der Sar is absent due to a knock on his knee he sustained in the 3-0 win against Everton on Saturday.